Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and is a major global health concern due to its high incidence and mortality rates. Research in this area focuses on understanding the underlying mechanisms of HCC development, progression, and treatment resistance, as well as identifying potential biomarkers for early diagnosis and novel therapeutic targets. Some key areas of research in HCC include studying the role of risk factors such as chronic viral hepatitis, alcohol consumption, and obesity in its development, investigating the genetic and epigenetic alterations that drive HCC tumor growth, and exploring the potential of immunotherapy and targeted therapies in improving patient outcomes. Overall, research in hepatocellular carcinoma aims to improve our understanding of this aggressive cancer and develop more effective strategies for its prevention, diagnosis, and treatment.